H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH

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H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH Basic information
Product Name:H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH
Synonyms:MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA;KINASE II (281-302);CAM Kinase II Inhibitor (281-302);CALMODULIN KINASE II INHIBITOR;CAM KINASE II 281-302;CAM KINASE II [ALA-286](281-302);CAM KINASE II INHIBITOR;[ALA286]-CA2+/CALMODULIN-DEPENDENT PROTEIN KINASE II (281-302)
CAS:141055-85-8
MF:C111H191N39O29S2
MW:2600.08
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Mol File:Mol File
H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH Structure
H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH Chemical Properties
density 1.47±0.1 g/cm3(Predicted)
storage temp. −20°C
SequenceMet-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala
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WGK Germany 3
MSDS Information
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SigmaAldrich English
H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH Usage And Synthesis
Uses[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) is a modified fragment of calcium/calmodulin-dependent protein kinase II that contains the active domain of CaMKII and has an alanine substitution at position 286. [Ala286]-Calmodulin-Dependent Protein Kinase II (281-302) can be used to develop more potent CaMKII inhibitors[1].
References[1] Ishida A, et al. Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin‐dependent protein kinase II[J]. FEBS letters, 1998, 427(1): 115-118. DOI:10.1016/s0014-5793(98)00405-0
H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH Preparation Products And Raw materials
Tag:H-Met-His-Arg-Gln-Glu-Ala-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-OH(141055-85-8) Related Product Information
AC2-12 H-LYS-SER-ASP-GLY-GLY-VAL-LYS-LYS-ARG-LYS-SER-SER-SER-SER-OH ASP-LEU-ASP-VAL-PRO-ILE-PRO-GLY-ARG-PHE-ASP-ARG-ARG-VAL-SER-VAL-ALA-ALA-GLU AC2-26 CALP2 CALMODULIN-DEPENDENT PROTEIN KINASE II (281-309) ITSFEEAKGLDRINERMPPRRDAMP CAM KINASE II CALMODULIN CALMODULIN