2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one

2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one Suppliers list

Company Name:	Shanghai YuanYe Biotechnology Co., Ltd.
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Company Name:	Tianjin Kailiqi Biotechnology Co., Ltd.
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Company Name:	Shanghai Hongye Biotechnology Co. Ltd
Tel:	400-9205774 400-920-5774
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2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one manufacturers

2-(4-CHLOROPHENYL)-4-(4-FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE
2026-07-10
CAS:219138-24-6
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000kg

2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one Basic information

Product Name:	2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one
Synonyms:	2-(4-CHLOROPHENYL)-4-(FLUOROPHENYL)-5-PYRIDIN-4-YL-1,2-DIHYDROPYRAZOL-3-ONE;P38 MAP KINASE INHIBITOR;2-(4-chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1H-pyrazol-3-one;p38 MAPK Inhibitor;p-38 MAPK Inhibitor,p38 MAPK Inhibitor;3H-Pyrazol-3-one, 2-(4-chlorophenyl)-4-(4-fluorophenyl)-1,2-dihydro-5-(4-pyridinyl)-;2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,2-dihydro-3H-pyrazol-3-one;p38 MAP Kinase Inhibitor, p38 MAPK inhibitor
CAS:	219138-24-6
MF:	C20H13ClFN3O
MW:	365.79
EINECS:
Product Categories:
Mol File:	Mol File

2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one Chemical Properties

Boiling point	534.1±60.0 °C(Predicted)
density	1.388±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMF: 5 mg/ml; DMSO: 5 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 0.3 mg/ml
form	A crystalline solid
pka	6.61±0.10(Predicted)
color	Light yellow to yellow
InChI	1S/C20H13ClFN3O/c21-15-3-7-17(8-4-15)25-20(26)18(13-1-5-16(22)6-2-13)19(24-25)14-9-11-23-12-10-14/h1-12,24H
InChIKey	DZFBYHUKZSRPHU-UHFFFAOYSA-N

Safety Information

WGK Germany	WGK 1
Storage Class	11 - Combustible Solids

MSDS Information

2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one Usage And Synthesis

Uses	p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM[1].
Biological Activity	Cell permeable: no', 'Product does not compete with ATP.', 'Reversible: no
IC 50	p38: 35 nM (IC₅₀)
References	[1] S E de Laszlo, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94. DOI:10.1016/s0960-894x(98)00495-8

2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one Preparation Products And Raw materials

Tag:2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,2-dihydropyrazol-3-one(219138-24-6) Related Product Information

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