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| | 3-Acetylpyridine adenine dinucleotide Basic information |
| Product Name: | 3-Acetylpyridine adenine dinucleotide | | Synonyms: | acetyldiphosphopyridine nucleotide;3-Acetylpyridine adenine dinucleotide, oxidised form 92+%;5'-ester with 3-acetyl-1-b-D-ribofuranosylpyridinium, inner salt;3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, REDUCED FORM;3-ACETYLPYRIDINE NAD;3-Acetylpyridine hypoxanthine dinucleotide，oxidized form;3-Acetyl-1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyridin-1-ium;acetylpyridineadeninedinucleotide | | CAS: | 86-08-8 | | MF: | C22H28N6O14P2 | | MW: | 662.44 | | EINECS: | 201-649-4 | | Product Categories: | nucleoside;Other | | Mol File: | 86-08-8.mol |  |
| | 3-Acetylpyridine adenine dinucleotide Chemical Properties |
| storage temp. | −20°C | | solubility | PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid | | color | White to light yellow | | biological source | Porcine brain | | Water Solubility | water: 50mg/mL, clear, colorless to faintly yellow | | InChIKey | KPVQNXLUPNWQHM-MFRNWTRNNA-N | | SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP([O-])(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=O)C)=C3)O2)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O |&1:1,2,3,15,16,17,19,32,r| |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HS Code | 2934999090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 3-Acetylpyridine adenine dinucleotide Usage And Synthesis |
| Description | 3-Acetylpyridine NAD (APAD) is an analog of NAD+ (free acid) (nicotinamide adenine dinucleotide; ), a signaling molecule and cofactor or substrate for many enzymes. APAD has been used to study the mechanisms of oxidative phosphorylation. It can be reduced by transdehydrogenase from NADH (sodium salt) . It can be reduced more efficiently and is more stable than NAD+; thus, it is useful as a substitute. | | Uses | 3-Acetylpyridine adenine dinucleotide, 90% is an analog of nicotinamide adenine dinucleotide (NAD). 33-Acetylpyridine adenine dinucleotide, 90% collaboratively inhibits Lactate Dehydrogenase (LDH) with bisulfite[1][2]. | | Definition | ChEBI: 3-acetylpyridine adenine dinucleotide is an organic molecular entity. | | References | [1] Boland MJ. NADH-dependent glutamate synthase from lupin nodules. Reactions with oxidised and reduced 3-acetylpyridine-adenine dinucleotide. Eur J Biochem. 1981 Apr;115(3):485-9. PMID:7238515
[2] Ciaccio EI. The inhibition of lactate dehydrogenase by 3-acetylpyridine adenine dinucleotide and bisulfite. J Biol Chem. 1966 Apr 10;241(7):1581-6. PMID:5946616 |
| | 3-Acetylpyridine adenine dinucleotide Preparation Products And Raw materials |
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