Diketone-PEG4-Biotin manufacturers
- Diketone-PEG4-Biotin
-
-
2025-06-07
- CAS:2353409-85-3
- Min. Order: 50mg
- Purity: >97.00%
- Supply Ability: 50mg
|
| | Diketone-PEG4-Biotin Basic information |
| Product Name: | Diketone-PEG4-Biotin | | Synonyms: | Diketone-PEG4-Biotin;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[15-[[4-(3,5-dioxohexyl)phenyl]amino]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]hexahydro-2-oxo-, (3aS,4S,6aR)- | | CAS: | 2353409-85-3 | | MF: | C33H50N4O9S | | MW: | 678.84 | | EINECS: | | | Product Categories: | | | Mol File: | 2353409-85-3.mol |  |
| | Diketone-PEG4-Biotin Chemical Properties |
| Boiling point | 945.0±65.0 °C(Predicted) | | density | 1.201±0.06 g/cm3(Predicted) | | pka | 9.09±0.10(Predicted) | | form | Oil | | color | Colorless to light yellow |
| | Diketone-PEG4-Biotin Usage And Synthesis |
| Uses | Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | Biological Activity | Diketone-PEG4-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | IC 50 | PEGs | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Diketone-PEG4-Biotin Preparation Products And Raw materials |
|