Pyrazol-1-yl-methanol manufacturers
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| | Pyrazol-1-yl-methanol Basic information |
| | Pyrazol-1-yl-methanol Chemical Properties |
| Melting point | 89-90℃ (ethanol water ) | | Boiling point | 214.0±23.0℃ (760 Torr) | | density | 1.21±0.1 g/cm3 (20 ºC 760 Torr) | | Fp | 83.2±22.6℃ | | storage temp. | Sealed in dry,Room Temperature | | pka | 13.14±0.10(Predicted) | | Appearance | White to off-white Solid |
| | Pyrazol-1-yl-methanol Usage And Synthesis |
| Synthesis | To a round-bottomed flask containing pyrazole (144 mmol, 100 g) and methanol (~200 mL), formaldehyde (131 g, 37% aqueous solution) was slowly added. The reaction mixture was stirred continuously at 25 °C for 4 h until a homogeneous solution (0193) was formed. Subsequently, the solvent was removed by distillation under reduced pressure and dried under vacuum for several hours to give the final 1-pyrazole methanol (127 g, 90% yield). | | References | [1] Patent: WO2016/191677, 2016, A1. Location in patent: Paragraph 0110 |
| | Pyrazol-1-yl-methanol Preparation Products And Raw materials |
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