N-[2-(3,4-Dihydroxyphenyl)ethyl]octadecanamide manufacturers
- STEARDA
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- $236.00
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2026-05-11
- CAS:105955-10-0
- Purity:
- Supply Ability: 10g
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| | N-[2-(3,4-Dihydroxyphenyl)ethyl]octadecanamide Basic information |
| | N-[2-(3,4-Dihydroxyphenyl)ethyl]octadecanamide Chemical Properties |
| storage temp. | Store at +4°C | | solubility | Soluble to 5 mM in ethanol with gentle warming | | form | Powder |
| | N-[2-(3,4-Dihydroxyphenyl)ethyl]octadecanamide Usage And Synthesis |
| Uses | STEARDA is a novel, endogenous capsaicin-like lipid that produces hyperalgesia. | | Definition | ChEBI: N-stearoyl dopamine is a carboxamide. It is functionally related to a dopamine. | | Biological Activity | Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB 1 receptors (at concentrations up to 5 μ M) and does not inhibit AMT or FAAH (IC 50 > 25 μ M). However, potentiates TRPV1-mediated effects of NADA in vitro and in vivo ; enhances effects on intracellular Ca 2+ (EC 50 lowered 3-fold) and nociception. Also inhibits arachidonate 5-lipoxygenase (IC 50 = 16 nM). |
| | N-[2-(3,4-Dihydroxyphenyl)ethyl]octadecanamide Preparation Products And Raw materials |
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