1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)-

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1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:ARRY-403
CAS:1138669-65-4
Purity:98.69% Package:1mg;988USD|5mg;1980USD|10mg;2670USD
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Products Intro: Product Name:ARRY-403
CAS:1138669-65-4
Purity:98% Package:1mg;5mg;10mg
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:ARRY-403
CAS:1138669-65-4
Purity:98.80% Package:1removed
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Email: Sales@sangon.com
Products Intro: Product Name:ARRY-403
CAS:1138669-65-4
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Tel: 13370042665 18916960931
Email: 2596183085@qq.com
Products Intro: Product Name:ARRY-403
CAS:1138669-65-4
Purity:5mg；25mg；1mg；10mg Package:98%

1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- manufacturers

  • ARRY-403
  • ARRY-403 pictures
  • $415.00
  • 2026-05-11
  • CAS:1138669-65-4
  • Purity: 98.80%
  • Supply Ability: 10g
1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- Basic information
Product Name:1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)-
Synonyms:1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)-
CAS:1138669-65-4
MF:C20H18N6O3S2
MW:454.53
EINECS:
Product Categories:
Mol File:1138669-65-4.mol
1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- Structure
1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- Chemical Properties
Boiling point 707.4±70.0 °C(Predicted)
density 1.54±0.1 g/cm3(Predicted)
pka11.24±0.20(Predicted)
Safety Information
MSDS Information
1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- Usage And Synthesis
UsesAMG-151 (ARRY-403) is a glucokinase agonist with fasting plasma glucose (FPG) lowering activity. AMG-151 showed a significant linear dose-response trend compared with placebo in a randomized, placebo-controlled Phase IIa study. The use of AMG-151 was associated with a higher incidence of hypoglycemia and hypertriglyceridemia. AMG-151 may serve as a potential compound for the inhibition of type 1 diabetes[1].
References[1] AMG 151 (ARRY-403), a novel glucokinase activator, decreases fasting and postprandial glycaemia in patients with type 2 diabetes
1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- Preparation Products And Raw materials
Tag:1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)-(1138669-65-4) Related Product Information
AMG151 HCl AR453588 1,2-Ethanediol, 1-[5-[[3-[(2-methyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)- AR453588 hydrochloride 1,2-Ethanediol, 1-[5-[[3-[(2,6-dimethyl-3-pyridinyl)oxy]-5-(2-pyridinylthio)-2-pyridinyl]amino]-1,2,4-thiadiazol-3-yl]-, (1S)-