Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester
概述 用途与合成方法 MSDS Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester价格(试剂级) 上下游产品信息
| 中文名称 | Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester |
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| 中文同义词 | 化合物MENIN-MLL INHIBITOR 20;(R)-4-[[3-(BOC-氨基)-1-哌啶基]甲基]-N-[4-(4-MORPHOLINO-7H-吡咯并[2,3-D]嘧啶-6-基)苯基]吡啶-2-甲酰胺;化合物MENIN-MLL INHIBITOR 20,10 MM DMSO 溶液;(R)-(1-((2-((4-(4-吗啉-7H-吡咯并[2,3-d]嘧啶-6-基)苯基)氨基甲酰基)吡啶-4-基)甲基)哌啶-3-基)氨基甲酸叔丁酯 |
| 英文名称 | Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester |
| 英文同义词 | Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester;Menin-MLL inhibitor 20,MRN73473;Menin-MLL inhibitor 20;Epigenetic Reader Domain,mixed-lineage,MeninMLL inhibitor 20,irreversible,leukemia,MLL,Inhibitor,antitumor,Menin MLL inhibitor 20,inhibit,Menin,Menin-MLL inhibitor 20;(R)-4-[[3-(Boc-amino)-1-piperidyl]methyl]-N-[4-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]pyridine-2-carboxamide;tert-butyl N-[(3R)-1-{[2-({4-[4-(morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl}carbamoyl)pyridin-4-yl]methyl}piperidin-3-yl]carbamate;Menin-MLL inhibitor 20, 10 mM in DMSO;(R)-tert-Butyl (1-((2-((4-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl)carbamoyl)pyridin-4-yl)methyl)piperidin-3-yl)carbamate |
| CAS号 | 2448173-47-3 |
| 分子式 | C33H40N8O4 |
| 分子量 | 612.72 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 2448173-47-3.mol |
| 结构式 | ![Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester 结构式](CAS/20210305/GIF/2448173-47-3.gif) |
Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester 性质
| 密度 | 1.34±0.1 g/cm3(Predicted) |
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| 储存条件 | Store at -20°C |
| 溶解度 | DMSO：33.33 mg/mL（54.40 mM；超声加热至 60°C） |
| 形态 | 固体 |
| 酸度系数(pKa) | 11.80±0.70(Predicted) |
| 颜色 | 浅黄至黄色 |
Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester 用途与合成方法
Menin-MLL inhibitor 20 是一种不可逆的 menin-MLL 相互作用的抑制剂，具有抗肿瘤活性 (WO2020142557A1, Intermediate 6)。
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-128798 | Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester Menin-MLL inhibitor 20 | 2448173-47-3 | 1 mg | 431元 |
| 2026/06/05 | HY-128798 | Carbamic acid, N-[(3R)-1-[[2-[[[4-[4-(4-morpholinyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]amino]carbonyl]-4-pyridinyl]methyl]-3-piperidinyl]-, 1,1-dimethylethyl ester Menin-MLL inhibitor 20 | 2448173-47-3 | 5mg | 1041元 |