Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]- manufacturers
- PHM16
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- $2500.00
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2026-07-27
- CAS:1448791-29-4
- Purity:
- Supply Ability: 10g
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| | Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]- Basic information |
| Product Name: | Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]- | | Synonyms: | Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]-;PHM 16;PHM16;PHM-16 | | CAS: | 1448791-29-4 | | MF: | C20H22N6O4 | | MW: | 410.43 | | EINECS: | | | Product Categories: | | | Mol File: | 1448791-29-4.mol | ![Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]- Structure](CAS/20210305/GIF/1448791-29-4.gif) |
| | Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]- Chemical Properties |
| density | 1.309±0.06 g/cm3(Predicted) | | pka | 14.67±0.46(Predicted) |
| | Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]- Usage And Synthesis |
| Description | PHM16 is an ATP competitive inhibitor of FAK and FGFR2. | | Uses | PHM16 is an ATP competitive inhibitor of FAK and FGFR2 (IC50: 0.4 μM and 0.37 μM, respectively), with direct potent anti-angiogenic activity[1]. | | IC 50 | FGFR2: 0.37 μM (IC50); FAK: 0.4 μM (IC50) | | References | [1] Pascal Dao, et al. Inhibition of both focal adhesion kinase and fibroblast growth factor receptor 2 pathways induces anti-tumor and anti-angiogenic activities. Cancer Lett. 2014 Jun 28;348(1-2):88-99. DOI:10.1016/j.canlet.2014.03.007 |
| | Benzamide, N-methyl-2-[[4-[(3,4,5-trimethoxyphenyl)amino]-1,3,5-triazin-2-yl]amino]- Preparation Products And Raw materials |
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