(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride

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(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride manufacturers
(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride Basic information
Product Name:(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride
Synonyms:(+/-)-DCMB HYDROCHLORIDE;LY-78335 HYDROCHLORIDE;1-(2,3-DICHLOROPHENYL)ETHAN-1-AMINE HYDROCHLORIDE;1-(2,3-Dichlorophenyl)ethanamine hydrochloride;3-Dichlorophenyl)ethanamine hydrochloride;2,3-dichloro-α-methylbenzylamine hydrochloride;(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride;(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride
CAS:39959-66-5
MF:C8H10Cl3N
MW:226.53
EINECS:
Product Categories:
Mol File:39959-66-5.mol
(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride Structure
(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride Chemical Properties
storage temp. Sealed in dry,Room Temperature
solubility H2O: Solutions may be stored for 1-2 days at 4 °C.soluble
form solid
color white
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride Usage And Synthesis
UsesLY 78335 is a phenylethanolamine N-methyl transferase inhibitor.
in vivo

1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats [1].

Animal Model:Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats[1]
Dosage:50 mg/kg
Administration:Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days
Result:Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.
(+/-)-2,3-Dichloro-alpha-methylbenzylamine hydrochloride Preparation Products And Raw materials
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