9H-Pyrido[3,4-b]indole-7-carboxylic acid, 1-[(cyclopropylcarbonyl)amino]-, methyl ester manufacturers
- ZDWX-25
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- $2500.00
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2026-07-27
- CAS:2668297-70-7
- Purity:
- Supply Ability: 10g
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| | 9H-Pyrido[3,4-b]indole-7-carboxylic acid, 1-[(cyclopropylcarbonyl)amino]-, methyl ester Basic information |
| | 9H-Pyrido[3,4-b]indole-7-carboxylic acid, 1-[(cyclopropylcarbonyl)amino]-, methyl ester Chemical Properties |
| Boiling point | 642.4±50.0 °C(Predicted) | | density | 1.476±0.06 g/cm3(Predicted) | | pka | 13.13±0.20(Predicted) |
| | 9H-Pyrido[3,4-b]indole-7-carboxylic acid, 1-[(cyclopropylcarbonyl)amino]-, methyl ester Usage And Synthesis |
| Uses | ZDWX-25 is a highly potent GSK-3β and DYRK1A dual inhibitor with an IC50 value of 71 nM for GSK-3β. ZDWX-25 possesses significant cytotoxic activities against SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for researching alzheimer's disease[1]. | | IC 50 | GSK-3β: 71 nM (IC50) | | References | [1] Liu W, et al. Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease. Eur J Med Chem. 2022;229:114095. DOI:10.1016/j.ejmech.2021.114095 |
| | 9H-Pyrido[3,4-b]indole-7-carboxylic acid, 1-[(cyclopropylcarbonyl)amino]-, methyl ester Preparation Products And Raw materials |
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