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| | VAPREOTIDE ACETATE Basic information |
| Product Name: | VAPREOTIDE ACETATE | | Synonyms: | VAPREOTIDE ACETATE;Vapreotide (RC160) acetate;Vapreotide acetate (1:x);BMY 41606 acetate;BMY41606 acetate;BMY-41606 acetate;RC 160 acetate;RC160 acetate | | CAS: | 849479-74-9 | | MF: | C59H74N12O11S2 | | MW: | 1191.43 | | EINECS: | | | Product Categories: | | | Mol File: | 849479-74-9.mol |  |
| | VAPREOTIDE ACETATE Chemical Properties |
| Melting point | 176-180°C | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | Acetic Acid (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Off-White | | Sequence | {d-Phe}-Cys-Tyr-{d-Trp}-Lys-Val-Cys-Trp-NH2 (Disulfide bridge: Cys2-Cys7) | | Stability: | Hygroscopic |
| | VAPREOTIDE ACETATE Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Vapreotide Acetate is a synthetic somatostatin (S676750) analog predominately used for the treatment of acute variceal bleeding. | | in vivo | In cirrhosis, bleeding by rupture of oesophagogastric varices is a severe complication of portal hypertension. The acute administration of vapreotide to rats decreases collateral circulation blood flow while chronic administration attenuated its development[4]. Tumor volumes and weights are reduced by about 40% by RC-160 by s.c. injections at doses of 100 μg/day/animal. Vapreotide can inhibit the growth of androgen-independent prostate cancer when the therapy is started at an early stage of tumor development[5]. | | IC 50 | NK1 |
| | VAPREOTIDE ACETATE Preparation Products And Raw materials |
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