2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-

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2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Suppliers list
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2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- manufacturers

  • COX-2-IN-22
  • COX-2-IN-22 pictures
  • $2500.00
  • 2026-05-11
  • CAS:2447589-08-2
  • Purity:
  • Supply Ability: 10g
2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Basic information
Product Name:2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-
Synonyms:2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-;COX-2-IN-22
CAS:2447589-08-2
MF:C29H24O7
MW:484.5
EINECS:
Product Categories:
Mol File:2447589-08-2.mol
2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Structure
2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Chemical Properties
Boiling point 706.8±60.0 °C(Predicted)
density 1.304±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Usage And Synthesis
UsesCOX-2-IN-22 (Compound 4h) is a COX-2 inhibitor with an IC50 of 8.6 μM. COX-2-IN-22 also inhibits AChE, BChE, β-Secretase, LOX-5 and DPPH with IC50 values of 2.8, 6.3, 15.3, 13.9 and 6.8 μM, respectively. COX-2-IN-22 can cross BBB[1].
IC 50AChE: 2.8 μM (IC50); BChE: 6.3 μM (IC50); DPPH: 6.8 μM (IC50); COX-2: 8.6 μM (IC50); LOX-5: 13.9 μM (IC50); β-Secretase: 15.3 μM (IC50)
References[1] Agbo EN, et al. Synthesis of furocoumarin-stilbene hybrids as potential multifunctional drugs against multiple biochemical targets associated with Alzheimer's disease. Bioorg Chem. 2020 Aug;101:103997. DOI:10.1016/j.bioorg.2020.103997
2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Preparation Products And Raw materials
Tag:2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-(2447589-08-2) Related Product Information
TRIOXSALEN 2H-Furo[2,3-h]-1-benzopyran-2-one, 8-(3,5-dimethoxyphenyl)-4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]- Gallic acid GYY 4137 Morpholine salt Deferiprone L-Epicatechin