Dynamin IN-2 manufacturers
- Dynamin IN-2
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- $143.00
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2026-07-29
- CAS:1345853-49-7
- Purity: 99.40%
- Supply Ability: 10g
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| | Dynamin IN-2 Basic information |
| Product Name: | Dynamin IN-2 | | Synonyms: | Dynamin IN-2;9H-Carbazole-9-ethanol, α-[[[(4-chlorophenyl)methyl]amino]methyl]-;Dynamin IN-2, 10 mM in DMSO | | CAS: | 1345853-49-7 | | MF: | C22H21ClN2O | | MW: | 364.87 | | EINECS: | | | Product Categories: | | | Mol File: | 1345853-49-7.mol |  |
| | Dynamin IN-2 Chemical Properties |
| Boiling point | 588.0±50.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | pka | 13.66±0.20(Predicted) |
| | Dynamin IN-2 Usage And Synthesis |
| Uses | Dynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM[1]. | | References | [1] Cossar PJ, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001. DOI:10.1016/j.ejmech.2022.115001 |
| | Dynamin IN-2 Preparation Products And Raw materials |
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