Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)-

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Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- manufacturers

  • RSV/IAV-IN-3
  • RSV/IAV-IN-3 pictures
  • $2500.00
  • 2026-07-27
  • CAS:2395007-81-3
  • Purity:
  • Supply Ability: 10g
Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- Basic information
Product Name:Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)-
Synonyms:Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)-;RSV/IAV-IN-3
CAS:2395007-81-3
MF:C19H19BrN2O3S
MW:435.33
EINECS:
Product Categories:
Mol File:2395007-81-3.mol
Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- Structure
Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- Chemical Properties
Boiling point 624.6±55.0 °C(Predicted)
density 1.51±0.1 g/cm3(Predicted)
pka12.92±0.70(Predicted)
Safety Information
MSDS Information
Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- Usage And Synthesis
UsesRSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC50 values of 2.92 μM and 1.90 μM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC50 values of 3.25 μM and 1.50 μM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC50 of 3.89 μM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage[1].
References[1] Guo-Ning Zhang, et al. Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A. Eur J Med Chem. 2020 Jan 15;186:111861. DOI:10.1016/j.ejmech.2019.111861
Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- Preparation Products And Raw materials
Tag:Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)-(2395007-81-3) Related Product Information
2-((1H-indol-3-yl)thio)-N-(2-ethoxyphenyl)acetamide Acetamide, 2-(1H-indol-3-ylthio)-N-(2-methoxyphenyl)- Acetamide, N-(2-ethoxyphenyl)-2-[(5-methoxy-1H-indol-3-yl)thio]- 2-((1H-indol-3-yl)thio)-N-(2,5-dimethoxyphenyl)acetamide Acetamide, 2-[(7-bromo-6-methoxy-1H-indol-3-yl)thio]-N-(2-ethoxyphenyl)- GLYCOPROTEIN/G protein, HRSV (258A.A, HEK293, HIS)