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| Product Name: | RXP03 | | Synonyms: | RXP03;Carbamic acid, [(1R)-1-[[(2S)-2-[[[(1S)-2-amino-1-(1H-indol-3-ylmethyl)-2-oxoethyl]amino]carbonyl]-5-phenylpentyl]hydroxyphosphinyl]-2-phenylethyl]-, phenylmethyl ester | | CAS: | 284667-65-8 | | MF: | C39H43N4O6P | | MW: | 694.76 | | EINECS: | | | Product Categories: | | | Mol File: | 284667-65-8.mol |  |
| | RXP03 Chemical Properties |
| Boiling point | 1055.520±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.286±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 2.811±0.50(predicted) |
| | RXP03 Usage And Synthesis |
| Uses | RXP03 is a MMPs inhibitor with the Ki of 20 nM, 2.5 nM, 10 nM, 5nM and 105 nM for MMP-2, MMP-8, MMP-9, MMP-11, MMP-14, respectively[1]. | | References | [1] Abdou MM, et al. Novel glycosyl prodrug of RXP03 as MMP-11 prodrug: design, synthesis and virtual screening. BMC Chem. 2023;17(1):167. Published 2023 Nov 25. DOI:10.1186/s13065-023-01075-1 |
| | RXP03 Preparation Products And Raw materials |
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