Patamostat HCl manufacturers
- Patamostat HCl
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- $117.00
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2026-07-31
- CAS:3031765-17-7
- Purity: 99.15%
- Supply Ability: 10g
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| | Patamostat HCl Basic information |
| Product Name: | Patamostat HCl | | Synonyms: | Patamostat HCl;Benzoic acid, 4-[(aminoiminomethyl)amino]-, 4-[[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]thio]phenyl ester, hydrochloride (1:1) | | CAS: | 3031765-17-7 | | MF: | C20H20N4O4S.ClH | | MW: | 448.92 | | EINECS: | | | Product Categories: | | | Mol File: | 3031765-17-7.mol |  |
| | Patamostat HCl Chemical Properties |
| | Patamostat HCl Usage And Synthesis |
| Uses | Patamostat hydrochloride is a potent protease inhibitor. Patamostat hydrochloride potently inhibits trypsin, plasmin and thrombin with IC50s of 39 nM, 950 nM and 1.9 μM, respectively. Patamostat hydrochloride may possess suppressing effects on pathogenesis and development of acute pancreatitis[1][2]. | | References | [1] K Miyamoto, et al. [Effects of E-3123, a New Protease Inhibitor, on Several Protease Activities and on Experimental Acute Pancreatitis]. Nihon Yakurigaku Zasshi. 1988 May;91(5):285-93. DOI:10.1254/fpj.91.285
[2] T Hirano, et al. Protective Effect of a Cephalosporin, Shiomarin, Plus a New Potent Protease Inhibitor, E3123, on Rat Taurocholate-Induced Pancreatitis. J Gastroenterol Hepatol. Jan-Feb 1993;8(1):52-9. DOI:10.1111/j.1440-1746.1993.tb01175.x |
| | Patamostat HCl Preparation Products And Raw materials |
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