| Company Name: |
Fuan Bio |
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15002819872 |
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2845971812@qq.com |
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| | Nisotirostide Basic information |
| | Nisotirostide Chemical Properties |
| solubility | DMSO: Soluble: = 10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/mlPBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml | | form | Solid | | color | White to off-white | | Sequence | Chain1:Pro-Lys-Pro-Glu-Lys-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Trp-Gln-Arg-Tyr-Tyr-Ala-Glu-Leu-Arg-His-Tyr-Leu-Asn-Trp-Leu-Thr-Arg-Gln-Arg-Tyr-NH2; Chain2:Ggu-Ggu-Oaa (Amide bridge:Chain1 Lys5-Chain2 Oaa3) |
| | Nisotirostide Usage And Synthesis |
| Uses | Nisotirotide (LY-3457263) is a PYY analog agonist studied in type 2 diabetes and obesity[1]. | | References | [1] Kloock S, et al. Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery Pharmacol Ther. 2023 Nov;251:108549. DOI:10.1016/j.pharmthera.2023.108549
[2] NICZE M, DEC A, BORÓWKA M, et al. Molecular Mechanisms behind Obesity and Their Potential Exploitation in Current and Future Therapy[J]. International Journal of Molecular Sciences, 2024, 169 1. DOI: 10.3390/ijms25158202 |
| | Nisotirostide Preparation Products And Raw materials |
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