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| | ARMEPAVINE Basic information |
| Product Name: | ARMEPAVINE | | Synonyms: | R-Armepavine;Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-;(R)-4-((6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)phenol;(-)-Armepavine | | CAS: | 524-20-9 | | MF: | C19H23NO3 | | MW: | 313.39 | | EINECS: | | | Product Categories: | Alkaloids | | Mol File: | 524-20-9.mol |  |
| | ARMEPAVINE Chemical Properties |
| Melting point | 149-150° | | alpha | D20 -117.6° (CHCl3) (Knabe); D27 -103.2° (Farber) | | Boiling point | 460.5±45.0 °C(Predicted) | | density | 1.151±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | Soluble in DMSO | | form | Solid | | pka | 9.99±0.15(Predicted) | | color | White to off-white |
| | ARMEPAVINE Usage And Synthesis |
| Uses | Armepavine, an active compound from Nelumbo nucifera, exerts not only anti-inflammatory effects on human peripheral blood mononuclear cells, but also immunosuppressive effects on T lymphocytes and on lupus nephritic mice. Armepavine inhibits TNF-α-induced MAPK and NF-κB signaling cascades[1]. | | Definition | ChEBI: Armepavine is a member of isoquinolines. | | IC 50 | p65 | | References | [1] Weng TC, et al. Inhibitory effects of armepavine against hepatic fibrosis in rats. J Biomed Sci. 2009 Sep 2;16:78. DOI:10.1186/1423-0127-16-78 |
| | ARMEPAVINE Preparation Products And Raw materials |
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