| Company Name: |
ChemOrigin Pharm |
| Tel: |
15026428026 19002516454 |
| Email: |
ChemOrigin@126.com |
|
| | JH-XII-03-02 Basic information |
| Product Name: | JH-XII-03-02 | | Synonyms: | JH-XII-03-02;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[15-[4-[6-[5-[(1-methylcyclopropyl)oxy]-1H-indazol-3-yl]-4-pyrimidinyl]-1-piperazinyl]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]amino]-;JH-XII-03-02 LRRK2 PROTAC degrader | | CAS: | 2415900-86-4 | | MF: | C43H51N9O10 | | MW: | 853.92 | | EINECS: | | | Product Categories: | | | Mol File: | 2415900-86-4.mol |  |
| | JH-XII-03-02 Chemical Properties |
| Boiling point | 1074.255±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.392±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 10.741±0.40(predicted) | | form | Solid | | color | Light yellow to yellow |
| | JH-XII-03-02 Usage And Synthesis |
| Uses | JH-XII-03-02 is a potent and selective LRRK2 PROTAC degrader. JH-XII-03-02 can be used for parkinson's Disease (PD) research[1]. | | References | [1] John M Hatcher, et al. Development of a highly potent and selective degrader of LRRK2. Bioorg Med Chem Lett. 2023 Oct 1;94:129449. DOI:10.1016/j.bmcl.2023.129449 |
| | JH-XII-03-02 Preparation Products And Raw materials |
|