2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]-

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2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]- Basic information
Product Name:2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]-
Synonyms:5-[(4-hydroxyphenyl)methylene]-2,4-Thiazolidinedione;5-(4-hydroxybenzylidene)-2,4-thiazolidinedione;2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]-;(Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-dione(WX180325);Pioglitazone Impurity 42;Pioglitazone impurity 5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione;(Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-dione
CAS:103788-60-9
MF:C10H7NO3S
MW:221.23
EINECS:
Product Categories:Drug Intermediates
Mol File:103788-60-9.mol
2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]- Structure
2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]- Chemical Properties
Safety Information
HazardClass IRRITANT
MSDS Information
2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]- Usage And Synthesis
Uses5-[(4-Hydroxyphenyl)methylene]-2,4-thiazolidinedione is a 5-Benzylidene-2,4-thiazolidenedione derivative designed as inhibitors of angiogenesis targeting VEGFR-2. Also, it is an intermediate used in the synthesis of MSDC 0602 (M755420), which is an analogue ofthiazolidinediones, exhibits low affinity for binding and activation of peroxisome proliferator-activated receptor γ (PPARγ). Thiazolidinediones are effective insulin-sensitizing drugs for treating various metabolic and inflammatory diseases.
2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]- Preparation Products And Raw materials
Preparation Products5-(4-(2-(3-Methoxyphenyl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione
Tag:2,4-Thiazolidinedione, 5-[(4-hydroxyphenyl)methylene]-(103788-60-9) Related Product Information
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