CST 626

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CST 626 Suppliers list
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
CST 626 Basic information
Product Name:CST 626
Synonyms:
CAS:3033993-13-1
MF:C61H82N8O9S
MW:1103.42
EINECS:
Product Categories:
Mol File:3033993-13-1.mol
CST 626 Structure
CST 626 Chemical Properties
Boiling point 1263.5±65.0 °C(predicted)
density 1.28±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka13.93±0.20(predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
CST 626 Usage And Synthesis
UsesCST626 (Compound 9) is a pan-IAP degrader PROTAC. CST626 degrades XIAP, cIAP1 and cIAP2 with DC50s of 0.7, 2.4, and 6.2 nM in MM.1S cells, respectively[1].
References[1] Ng YLD, et al. Heterobifunctional Ligase Recruiters Enable pan-Degradation of Inhibitor of Apoptosis Proteins. J Med Chem. 2023 Apr 13;66(7):4703-4733. DOI:10.1021/acs.jmedchem.2c01817
CST 626 Preparation Products And Raw materials
Tag:CST 626(3033993-13-1) Related Product Information
Protac linker 5 VH 032-linker 8 (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide hydrochloride (S,R,S)-AHPC-C10-NH2 dihydrochloride (S,R,S)-Ahpc-C4-NH2 VH032-O-Ph-PEG1-NH2