Protac linker 5

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:(S,R,S)-AHPC-C4-NH2 hydrochloride
CAS:2245697-83-8
Purity:95.05% Package:5mg;32USD|10mg;39USD|25mg;64USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Henan Alfa Chemical Co., Ltd
Tel: +8615838112936
Email: sale03@alfachem.cn
Products Intro: CAS:2245697-83-8
Purity:98% Package:5g; 25g; 100g; 500g; 1kg; 25kg
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:Protac linker 5
CAS:2245697-83-8
Purity:98% Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Shanxi Tihondan Pharmaceutical Technology Co., Ltd
Tel: +8618235132063
Email: sales@tihondan.com
Products Intro: Product Name:(2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
CAS:2245697-83-8
Purity:95%+ Package:5g;10g;1kg;10kg
Company Name: ChemShuttle, Inc.  
Tel: 0510-83588313-811 18800520310
Email: sales@chemshuttle.com
Products Intro: Product Name:(2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
CAS:2245697-83-8
Purity:95% Package:5mg;25mg;100mg;500mg;1g;5g;10g;25g;50g;100g;250g;500g;kg…

Protac linker 5 manufacturers
Protac linker 5 Basic information
Product Name:Protac linker 5
Synonyms:Protac linker 5;E3 ligase Ligand-Linker Conjugates 28;(S,R,S)-AHPC-C3-NH2;VH032-C4-NH2 hydrochloride;VHL Ligand-Linker Conjugates 13;inhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydrochloride,Inhibitor,(S,R,S) AHPC C4 NH2 hydrochloride
CAS:2245697-83-8
MF:C27H40ClN5O4S
MW:566.16
EINECS:
Product Categories:
Mol File:2245697-83-8.mol
Protac linker 5 Structure
Protac linker 5 Chemical Properties
form Solid
color Light yellow to green yellow
Safety Information
MSDS Information
Protac linker 5 Usage And Synthesis
Uses(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].
IC 50VHL
References[1] Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. DOI:10.1016/j.chembiol.2019.11.004
Protac linker 5 Preparation Products And Raw materials
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