| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Diosbulbin C
CAS:20086-07-1
Purity:98.5% Package:5mg Remarks:BBP01051
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| | Diosbulbin C Basic information |
| Product Name: | Diosbulbin C | | Synonyms: | Diosbulbin C;(2R)-2-(3-Furyl)-1,2,6,6aβ,7,8,9,10,10aα,10b-decahydro-9α-hydroxy-10bβ-methyl-4-oxo-4H-3aβ,6β-methanofuro[2,3-d][2]benzoxepine-7α-carboxylic acid;Airpotato yam C;4H-3a,6-Methanofuro[2,3-d][2]benzoxepin-7-carboxylic acid, 2-(3-furanyl)decahydro-9-hydroxy-10b-methyl-4-oxo-, (2R,3aS,6S,6aS,7R,9R,10aR,10bS)- | | CAS: | 20086-07-1 | | MF: | C19H22O7 | | MW: | 362.37 | | EINECS: | | | Product Categories: | | | Mol File: | 20086-07-1.mol |  |
| | Diosbulbin C Chemical Properties |
| Melting point | 247-250 °C | | Boiling point | 606.0±55.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 4.36±0.70(Predicted) |
| | Diosbulbin C Usage And Synthesis |
| Uses | Diosbulbin C is a diterpene lactone component, which can be extracted from traditional Chinese medicine Dioscorea bulbifera L.. Diosbulbin C possesses high anticancer activity in non-small cell lung cancer (NSCLC). Diosbulbin C could induce cell cycle arrest at G0/G1 phase in NSCLC. Diosbulbin C also inhibits the proliferation of NSCLC cells, possibly by downregulating the expression/activation of AKT, DHFR, and TYMS[1][1]. | | Definition | ChEBI: Diosbulbin C is a naphthofuran. | | References | [1] Zhu Z, et al. Diosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest. BMC Complement Med Ther. 2023 Dec 4;23(1):436. DOI:10.1186/s12906-023-04245-9 |
| | Diosbulbin C Preparation Products And Raw materials |
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