|
|
| | β-Cembrenediol Basic information |
| Product Name: | β-Cembrenediol | | Synonyms: | β-Cembrenediol;(+)-β-Cembratrienediol;(1E,3R,5R,6E,10E,14S)-14-Isopropyl-3,7,11-trimethylcyclotetradeca-1,6,10-triene-3,5-diol;(1R,3R,4E,8E,12S,13E)-1,5,9-Trimethyl-12-(1-methylethyl)-4,8,13-cyclotetradecatriene-1,3-diol;Cembratriene-4,6-diol;beta-CeMbrenediol;(1S,2E,4R,6R,7E,11E)-2,7,11-Cembratriene-4,6-diol;β-4,8,13-Duvatriene-1,3-diol | | CAS: | 57605-81-9 | | MF: | C20H34O2 | | MW: | 306.48 | | EINECS: | | | Product Categories: | | | Mol File: | 57605-81-9.mol |  |
| | β-Cembrenediol Chemical Properties |
| Melting point | 106-112°C | | Boiling point | 431.8±45.0 °C(Predicted) | | density | 0.932±0.06 g/cm3(Predicted) | | storage temp. | Amber Vial, -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 14.13±0.70(Predicted) | | color | White to Off-White | | Stability: | Light Sensitive |
| | β-Cembrenediol Usage And Synthesis |
| Uses | β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments. | | in vivo | β-Cembrenediol (15 mg/kg; p.o.; daily for 8 weeks) shows anti-tumor activity in prostate cancer mice[2]. | Animal Model: | Male athymic nude mice (PC-3M PC cells)[2] | | Dosage: | 15 mg/kg | | Administration: | P.o.; daily for 8 weeks | | Result: | Significantly suppressed the development, extended the latency, and delayed the onset of the locoregional PC-3M cell tumor recurrence, reduced mice plasma total prostate-specific antigen and plasma kynurenine level. |
|
| | β-Cembrenediol Preparation Products And Raw materials |
|