| Company Name: |
GL Biochem (Shanghai) Ltd
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| Tel: |
21-61263452 13641803416 |
| Email: |
ymbetter@glbiochem.com |
| Products Intro: |
Product Name:Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2
CAS:891198-38-2
Purity:95% HPLC,98% HPLC Package:10mg, 25mg, 50mg, 100mg, 500mg, 1g,10g
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| | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 Basic information |
| Product Name: | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 | | Synonyms: | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2;Mca-PLGLEEA-Dap(Dnp)-NH2;L-Alaninamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]- (9CI);L-Alaninamide,1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]-;MATRIX METALLOPROTEINASE MMP-12 FRET substrate;390 MMP FRET Substrate 5 - 1 mg;Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap (Dnp)-NH2 trifluoroacetate salt | | CAS: | 891198-38-2 | | MF: | C53H70N12O20 | | MW: | 1195.19 | | EINECS: | | | Product Categories: | | | Mol File: | 891198-38-2.mol |  |
| | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 Chemical Properties |
| density | 1.387±0.06 g/cm3 | | Appearance | Yellow Powder | | Sequence | {Mca}-Pro-Leu-Gly-Leu-Glu-Glu-Ala-{Dap(Dnp)}-NH2 |
| | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 Usage And Synthesis |
| Description | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is a highly selective MMP-12 FRET substrate with a kcat/Km value of 1.85·105 M-1s-1. It is a poor substrate of other MMPs with the exception of MMP-13 (kcat/Km = 0.53·105 M-1s-1) and MMP-9 (kcat/Km = 0.33·105 M-1s-1). | | Uses | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is highly selective substrate for matrix metalloproteases 12 (MMP12) substrate with a kcat/Km value of 1.85*105 M-1s-1, and poor substrate of other MMPs with the exception of MMP13 (kcat/Km = 0.53*105 M-1s-1) and MMP9 (0.33*105 M-1s-1)[1]. | | References | [1] Sarah Bregant, et al. Detection of matrix metalloproteinase active forms in complex proteomes: evaluation of affinity versus photoaffinity capture. J Proteome Res. 2009 May;8(5):2484-94. DOI:10.1021/pr801069c | | Sequene | Mca-PLGLEEA-Dpa-NH2 |
| | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 Preparation Products And Raw materials |
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