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| | Aminopeptidase N/CD13 (C-Term) Rabbit Monoclonal Antibody (RM403) Basic information |
| | Aminopeptidase N/CD13 (C-Term) Rabbit Monoclonal Antibody (RM403) Chemical Properties |
| | Aminopeptidase N/CD13 (C-Term) Rabbit Monoclonal Antibody (RM403) Usage And Synthesis |
| Description | Aminopeptidase N, also known as cluster of differentiation 13 (CD13), is a zinc-dependent and membrane-bound ectopeptidase and type II membrane glycoprotein encoded by ANPEP in humans.1,2 It is composed of a short N-terminal cytosolic domain, a membrane-spanning domain, and five extracellular domains, including a C-terminal catalytic domain.2,3 It is ubiquitously expressed on cell membranes where it functions as a dimer to degrade peptides and proteins containing N-terminal neutral amino acids.2 Plasma levels of soluble aminopeptidase N are increased and positively correlated with tumor progression in patients with non-small cell lung cancer (NSCLC).1 ANPEP is overexpressed in psoriatic skin lesions, synovial fibroblasts isolated from patients with rheumatoid arthritis, and lymphocytes and peripheral blood mononuclear cells (PBMCs) isolated from patients with multiple sclerosis during acute exacerbation and chronic progression.2 Cayman’s Aminopeptidase N/CD13 (C-Term) Rabbit Monoclonal Antibody (RM403) can be used for immunohistochemistry (IHC) and Western blot (WB) applications.WARNING This product is not for human or veterinary use. |
| | Aminopeptidase N/CD13 (C-Term) Rabbit Monoclonal Antibody (RM403) Preparation Products And Raw materials |
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