TRIS SUCCINATE

TRIS SUCCINATE Suppliers list
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +86-13203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:TRIS SUCCINATE
CAS:84540-64-7
Purity:95.0% windy120 Package:5KG;2KG
Company Name: Spectrum Chemical Manufacturing Corp.  
Tel: 021-021-021-67601398-809-809-809 15221380277
Email: marketing_china@spectrumchemical.com
Products Intro: Product Name:Tris(hydroxyMethyl)aMinoMethane Succinate
CAS:84540-64-7
Package:25GM Remarks:T1417
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Email: chenjw@absin.cn
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Company Name: Apollo Scientific Ltd.  
Tel: 44 161 406 0505
Email: sales@apolloscientific.co.uk
Products Intro: CAS:84540-64-7
Purity:>98% Package:£24.00/50g;£58.00/250g Remarks:BIT3096
Company Name: Acros Organics  
Tel: +32 14/57.52.11
Email: info@acros.com
Products Intro: Purity:99% Package:250GR
TRIS SUCCINATE Basic information
Product Name:TRIS SUCCINATE
Synonyms:DI[TRIS(HYDROXYMETHYL)AMINOMETHANE] SUCCINATE;TRIS(HYDROXYMETHYL)AMINOMETHANE SUCCINATE;TRIS SUCCINATE;TRIZMA SUCCINATE;Tris(hydroxymethyl)aminomethane succinate >98%;Tris-succinate,99%;2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL SUCCINATE;succinic acid, compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
CAS:84540-64-7
MF:C12H28N2O10
MW:360.36
EINECS:283-159-0
Product Categories:buffer
Mol File:84540-64-7.mol
TRIS SUCCINATE Structure
TRIS SUCCINATE Chemical Properties
Melting point 138-141 °C
Safety Information
Safety Statements 24/25
HS Code 2921490090
MSDS Information
ProviderLanguage
ACROS English
TRIS SUCCINATE Usage And Synthesis
Chemical PropertiesWhite granular or crystalline powder
UsesSuccinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[1][2][3].
in vivo

Succinic acid tromethamine (3, 6 mg/kg; p.o.) increases the percentage of entries into open arms and of time spent on open arms in male mice[3].
Succinic acid tromethamine (3, 6, 12 mg/kg; i.p.) significant increases in food intake during 5 min, and 40 min after drug administration rectal temperature was measured, succinic acid at a dose of 1.5 mg/kg, inhibited stress-induced hyperthermia[3].

IC 50Microbial Metabolite; Human Endogenous Metabolite
References[1] Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10. DOI:10.1631/jzus.B1100134
[2] A T JOHNS, et al. The production of propionic acid by decarboxylation of succinic acid in a bacterial fermentation. Biochem J. 1948;42(1):ii. PMID:18934530
[3] Si Wei Chen, Anxiolytic-like effect of succinic acid in mice. Life Sci. 2003 Nov 7;73(25):3257-64. DOI:10.1016/j.lfs.2003.06.017
TRIS SUCCINATE Preparation Products And Raw materials
Tag:TRIS SUCCINATE(84540-64-7) Related Product Information
TRIS SUCCINATE Tris(hydroxymethyl)aminomethane acetate salt TRIZMA CITRATE DIBASIC TRIZMA CITRATE TRIBASIC TRIS SUCCINATE