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| | CUBEBIN Basic information |
| Product Name: | CUBEBIN | | Synonyms: | CUBEBIN;tetrahydro-3,4-dipiperonylfuran-2-ol;CUBEBIN(RG);3,4-Bis[(1,3-benzodioxol-5-yl)methyl]tetrahydrofuran-2-ol;[[3R,(-)]-3α,4β-Bis[(1,3-benzodioxole-5-yl)methyl]tetrahydrofuran]-2-ol;.beta.-Cubebin;2-Furanol, 3,4-bis(1,3-benzodioxol-5-ylmethyl)tetrahydro-, (2S,3R,4R)-;2-Furanol, tetrahydro-3,4-dipiperonyl- | | CAS: | 18423-69-3 | | MF: | C20H20O6 | | MW: | 356.37 | | EINECS: | 242-300-6 | | Product Categories: | Heterocycles | | Mol File: | 18423-69-3.mol |  |
| | CUBEBIN Chemical Properties |
| Melting point | 131-132°C | | alpha | D14 -17° (acetone) | | Boiling point | 409.21°C (rough estimate) | | density | 1.2029 (rough estimate) | | refractive index | 1.4450 (estimate) | | pka | 13.04±0.60(Predicted) | | LogP | 3.340 (est) |
| | CUBEBIN Usage And Synthesis |
| Uses | Cubebin is a dibenzylbutyrolactone lignan isolated from the crude hexane extract of the leaves of Zanthoxyllum naranjillo. Cubebin shows a significant anti-inflammatory activity[1]. | | Definition | ChEBI: A lignan that consists of tetrahydrofuran-2-ol substituted by two 1,3-benzodioxol-5-ylmethyl groups at positions 3 and 4 respectively (the 2S,3R,4R stereoisomer). It is isolated from the leaves of Pi
er nigrum and exhibits analgesic, anti-inflammatory, antimicrobial and trypanocidal activities. | | References | [1] Bastos JK, et al. Anti-inflammatory activity of cubebin, a lignan from the leaves of Zanthoxyllum naranjillo Griseb. J Ethnopharmacol. 2001;75(2-3):279-282. DOI:10.1016/s0378-8741(01)00171-4 |
| | CUBEBIN Preparation Products And Raw materials |
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