17-phenoxy trinor Prostaglandin F2α isopropyl ester

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17-phenoxy trinor Prostaglandin F2α isopropyl ester Basic information
Product Name:17-phenoxy trinor Prostaglandin F2α isopropyl ester
Synonyms:17-phenoxy trinor Prostaglandin F2α isopropyl ester
CAS:
MF:
MW:0
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Mol File:Mol File
17-phenoxy trinor Prostaglandin F2α isopropyl ester Structure
17-phenoxy trinor Prostaglandin F2α isopropyl ester Chemical Properties
solubility DMF: 100 mg/ml
DMSO: 100 mg/ml
Ethanol: 100 mg/mlPBS (pH 7.2): 1 mg/ml
Safety Information
MSDS Information
17-phenoxy trinor Prostaglandin F2α isopropyl ester Usage And Synthesis
DescriptionThe actions of many clinical F-series prostaglandins (PGs), including those used for estrous synchronization and reduction of intraocular pressure (IOP), are mediated through the PGF2α (FP) receptor.1,2,3 17-phenoxy PGF2α isopropyl ester is an analog of PGF2α containing a 17-phenoxy group on the lower side chain and an isopropyl ester at the C-1 position. There are no published reports on the biological activity of 17-phenoxy PGF2α isopropyl ester.WARNING This product is not for human or veterinary use.
References[1] S NARUMIYA  F U  Y Sugimoto. Prostanoid receptors: structures, properties, and functions.[J]. Physiological reviews, 1999, 79 4: 1193-1226. DOI: 10.1152/physrev.1999.79.4.1193
[2] BAHRAM RESUL PHD  Johan S M, PHD  Laszlo B P  Goran Selén Phd. Structure-activity relationships and receptor profiles of some ocular hypotensive prostanoids[J]. Survey of ophthalmology, 1997, 41: Pages S47-S52. DOI: 10.1016/s0039-6257(97)80007-0
[3] ABBOT F. CLARK  Thomas Y. Ophthalmic drug discovery[J]. Nature Reviews. Drug Discovery, 2003, 2 6: 448-459. DOI: 10.1038/nrd1106
17-phenoxy trinor Prostaglandin F2α isopropyl ester Preparation Products And Raw materials
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