16-phenoxy tetranor Prostaglandin F2α isopropyl ester

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16-phenoxy tetranor Prostaglandin F2α isopropyl ester Basic information
Product Name:16-phenoxy tetranor Prostaglandin F2α isopropyl ester
Synonyms:16-phenoxy tetranor Prostaglandin F2α isopropyl ester;16-phenoxy tetranor Prostaglandin F2.alpha. isopropyl ester;16-phenoxy tetranor Prostaglandin F2α isopropyl ester Exclusive;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-
CAS:130209-78-8
MF:C25H36O6
MW:432.55
EINECS:
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Mol File:130209-78-8.mol
16-phenoxy tetranor Prostaglandin F2α isopropyl ester Structure
16-phenoxy tetranor Prostaglandin F2α isopropyl ester Chemical Properties
Boiling point 577.8±50.0 °C(Predicted)
density 1.173±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): .5 mg/ml
pka13.57±0.20(Predicted)
Safety Information
MSDS Information
16-phenoxy tetranor Prostaglandin F2α isopropyl ester Usage And Synthesis
DescriptionProstaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α isopropyl ester (16-phenoxy tetranor PGF2α isopropyl ester) is a lipophilic analog of 16-phenoxy tetranor PGF2α. Isopropyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Uses15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments[1].
16-phenoxy tetranor Prostaglandin F2α isopropyl ester Preparation Products And Raw materials
Tag:16-phenoxy tetranor Prostaglandin F2α isopropyl ester(130209-78-8) Related Product Information
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