KRX-0501

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KRX-0501 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
KRX-0501 Basic information
Product Name:KRX-0501
Synonyms:KRX-0501;Cyclohexanol, 4-[[2-aMino-5-[(4-chlorophenyl)ethynyl]-4-pyriMidinyl]aMino]-, trans- (9CI);KP 544;XBVOXAWRUIZEMG-WKILWMFISA-N
CAS:393856-87-6
MF:C18H19ClN4O
MW:342.82
EINECS:
Product Categories:
Mol File:393856-87-6.mol
KRX-0501 Structure
KRX-0501 Chemical Properties
Boiling point 618.501±65.00 °C(Press: 760.00 Torr)(predicted)
density 1.364±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka15.013±0.40(predicted)
Safety Information
MSDS Information
KRX-0501 Usage And Synthesis
UsesKP 544 is a potent neurotrophic protein enhancer that amplifies nerve growth factor (NGF)-induced neurite outgrowth of PC12 cells and SH-SY5Y neuroblastoma cells. KP544 also enhances choline acetyltransferase activity. KP 544 selectively interact in the differentiation pathway downstream of MAPK in a manner that amplifies nerve growth factor and cyclic AMP effects and is also neuroprotective[1].
References[1] Fyfe J A, et al. KP544 amplifies the effects of nerve growth factor on cell differentiation and is neuroprotective[J]. Drug development research, 2004, 62(1): 49-59.
KRX-0501 Preparation Products And Raw materials
Tag:KRX-0501(393856-87-6) Related Product Information
Cyclohexanol, 4-[[5-(2-phenylethynyl)-4-pyrimidinyl]amino]-, trans- 4-Piperidinol, 1-[2-amino-5-(2-phenylethynyl)-4-pyrimidinyl]- 4-Piperidinol, 1-[2-amino-5-[2-(4-chlorophenyl)ethynyl]-4-pyrimidinyl]- 4-Piperidinol, 1-[5-[2-(4-chlorophenyl)ethynyl]-4-pyrimidinyl]- Ethanol, 2-[[2-amino-5-[2-(4-chlorophenyl)ethynyl]-4-pyrimidinyl]amino]- KRX-0501