10-乙酰基-3,7-二羟基吩嗪
| 中文名称 | 10-乙酰基-3,7-二羟基吩嗪 |
|---|---|
| 中文同义词 | 10-乙酰基-3,7-二羟基吩嗪;10-乙酰基-3,7-二羟基吩噁嗪;1-(3,7-二羟基-10H-吩恶嗪-10-基)乙酮;荧光底物-10-乙酰基-3,7-二羟基吩嗪;10-乙酰基-3;7-二羟基吩噁嗪;荧光红染料;10-乙酰基-3,7-二羟基吩嗪,刃天青红 |
| 英文名称 | 10-Acetyl-3,7-dihydroxyphenoxazine |
| 英文同义词 | AMPLIFLU RED;AMPLEX(R) RED REAGENT;10-ACETYL-3,7-DIHYDROXYPHENOXAZINE [ADHP];10-ACETYL-3,7-DIHYDROXYPHENOXAZINE,99%;10-Acetyl-3,7-dihydroxypenoxazin;Amplisyn Red, 99%;1-(3,7-Dihydroxy-10H-phenoxazin-10-yl)ethanone;ADHP [10-Acetyl-3,7-dihydroxyphenoxazine] |
| CAS号 | 119171-73-2 |
| 分子式 | C14H11NO4 |
| 分子量 | 257.24 |
| EINECS号 | |
| 相关类别 | 自有品牌试剂;荧光染料;试剂盒-细胞分析试剂盒;合成材料中间体;探针;酶底物;小分子 |
| Mol文件 | 119171-73-2.mol |
| 结构式 |  |
10-乙酰基-3,7-二羟基吩嗪 性质
| 熔点 | >250 °C (decomp) |
|---|---|
| 沸点 | 618.6±55.0 °C(Predicted) |
| 密度 | 1.459±0.06 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | DMF：25mg/mL； DMSO：25mg/mL； DMSO:PBS (pH 7.2)1:5：0.15 mg/ml；乙醇：1.5mg/mL |
| 形态 | 结晶固体 |
| 酸度系数(pKa) | 9.41±0.20(Predicted) |
| 颜色 | 浅棕色至棕色 |
| 激发峰(Ex)/发射峰(Em) | λex 571 nm; λem 584 nm |
| InChI | InChI=1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3 |
| InChIKey | PKYCWFICOKSIHZ-UHFFFAOYSA-N |
| SMILES | C(=O)(N1C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2)C |
To obtain the parameters K m and k cat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H 2 O 2 to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a K m of 31±4 μM and the k cat of 186± 6 s −1 .The k obs also increases over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second order rate constant obtain from the slope of k obs against ADHP concentration K app on is 2.1±0.2 mM/s.
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/10/13 | XW0111917173202 | 荧光红染料 Ampliflu Red | 119171-73-2 | 5mg | 650元 |
| 2026/09/15 | HY-101880 | 10-乙酰基-3,7-二羟基吩嗪 ADHP | 119171-73-2 | 1 mg | 195元 |