5-(9-ISOPROPYL-2-MORPHOLINO-9H-PURIN-6-YL)PYRIMIDIN-2-AMINE
| 中文名称 | 5-(9-ISOPROPYL-2-MORPHOLINO-9H-PURIN-6-YL)PYRIMIDIN-2-AMINE |
|---|---|
| 中文同义词 | 5-[9-异丙基-2-(4-吗啉基)-9H-嘌呤-6-基]-2-嘧啶胺;化合物DESMETHYL-VS-5584;Desmethyl-VS-5584 5mg试剂;Desmethyl-VS-5584 5mg试剂 |
| 英文名称 | 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine |
| 英文同义词 | Desmethyl-VS-5584;5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine;5-[9-(1-Methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine;5-[2-(morpholin-4-yl)-9-(propan-2-yl)-9H-purin-6-yl]pyrimidin-2-amine;DESMETHYL VS 5584; DESMETHYL VS5584;2-Pyrimidinamine, 5-[9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-;VS-5584 analog;Desmethyl-SB2343,Dual inhibitor,Selectivity,DesmethylVS5584,Mammalian target of Rapamycin,PI3K,Phosphoinositide 3-kinase,mTOR,Inhibitor,Desmethyl VS 5584,inhibit |
| CAS号 | 1246535-95-4 |
| 分子式 | C16H20N8O |
| 分子量 | 340.38 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1246535-95-4.mol |
| 结构式 |  |
5-(9-ISOPROPYL-2-MORPHOLINO-9H-PURIN-6-YL)PYRIMIDIN-2-AMINE 性质
| 沸点 | 669.3±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.52±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 氯仿：0.5mg/mL |
| 形态 | 固体 |
| 酸度系数(pKa) | 3.94±0.10(Predicted) |
Desmethyl-VS-5584 是 VS-5584 的二甲基类似物，VS-5584 是一种具有吡啶 [2,3-d] 嘧啶结构的有效且有选择性 mTOR/PI3K 双重抑制剂。