| Company Name: |
SPIRO PHARMA |
| Tel: |
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| Email: |
eric_feng1954@126.com |
Mutant EGFR inhibitor manufacturers
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| | Mutant EGFR inhibitor Basic information |
| Product Name: | Mutant EGFR inhibitor | | Synonyms: | Mutant EGFR inhibitor;N-[5-[[5-Chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-2-propenamide;MDK3627;2-Propenamide, N-[5-[[5-chloro-4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[[2-(dimethylamino)ethyl]methylamino]-4-methoxyphenyl]-;ABM-3627;ErbB-1,HER1,inhibit,EGFR,Inhibitor,Mutant EGFR inhibitor,Epidermal growth factor receptor;N-(5-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide;Mutant EGFR inhibitor, 10 mM in DMSO | | CAS: | 1421373-62-7 | | MF: | C27H30ClN7O2 | | MW: | 520.03 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1421373-62-7.mol |  |
| | Mutant EGFR inhibitor Chemical Properties |
| density | 1.316±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder | | pka | 12.66±0.70(Predicted) | | color | Light yellow to yellow |
| | Mutant EGFR inhibitor Usage And Synthesis |
| Uses | Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M. | | IC 50 | EGFRL858R; EGFRExon 19 deletion; EGFRT790M | | References | [1] WO 2013014448 A1 |
| | Mutant EGFR inhibitor Preparation Products And Raw materials |
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