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| | N-(2-Aminoethyl)piperidine Basic information |
| Product Name: | N-(2-Aminoethyl)piperidine | | Synonyms: | 2-(1-Piperidinyl)ethanamine;2-(1-Piperidinyl)ethylamine;Piperidine, 1-(2-aminoethyl)-;LABOTEST-BB LT02100617;1-PIPERIDINE ETHYLAMINE;2-(1-PIPERIDINO)ETHYLAMINE;2-PIPERIDINOETHYLAMINE;2-PIPERIDIN-1-YL-ETHYLAMINE | | CAS: | 27578-60-5 | | MF: | C7H16N2 | | MW: | 128.22 | | EINECS: | 248-540-8 | | Product Categories: | API intermediates | | Mol File: | 27578-60-5.mol |  |
| | N-(2-Aminoethyl)piperidine Chemical Properties |
| Melting point | 67-70 °C(Solv: ligroine (8032-32-4); dichloromethane (75-09-2)) | | Boiling point | 186 °C(lit.) | | density | 0.899 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.473(lit.) | | Fp | 136 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | Liquid | | pka | pK1: 6.38;pK2: 9.89 (30°C) | | color | Clear colorless to yellow | | Water Solubility | Partly miscible in water. | | Sensitive | Air Sensitive | | BRN | 103469 | | InChI | InChI=1S/C7H16N2/c8-4-7-9-5-2-1-3-6-9/h1-8H2 | | InChIKey | CJNRGSHEMCMUOE-UHFFFAOYSA-N | | SMILES | N1(CCN)CCCCC1 | | CAS DataBase Reference | 27578-60-5(CAS DataBase Reference) | | NIST Chemistry Reference | 1-Piperidineethanamine(27578-60-5) |
| Hazard Codes | C,Xi | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 2734 8/PG 2 | | WGK Germany | 3 | | Hazard Note | Irritant | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29333990 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Flam. Liq. 3
Skin Corr. 1B |
| | N-(2-Aminoethyl)piperidine Usage And Synthesis |
| Chemical Properties | CLEAR COLOURLESS TO YELLOW LIQUID | | Uses | 1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand. | | General Description | 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand. |
| | N-(2-Aminoethyl)piperidine Preparation Products And Raw materials |
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