beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt manufacturers
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| | beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt Basic information |
| Product Name: | beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt | | Synonyms: | 1,3,5(10)-ESTRATRIENE-3,17BETA-DIOL 17-PENTANOATE;1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 17-VALERATE;1,3,5(10)-ESTRATRIEN-3,17B-DIOL-17-VALERATE;1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 17-VALERATE;17B-ESTRADIOL-17-VALERATE;17B-ESTRADIOL VALERATE;17BETA-ESTRADIOL VALERATE;17-BETA-ESTRADIOL 17-VALERATE | | CAS: | 10392-35-5 | | MF: | C24H33KO11S | | MW: | 568.68 | | EINECS: | 213-559-2 | | Product Categories: | Glucuronides;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | | Mol File: | 10392-35-5.mol |  |
| | beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt Chemical Properties |
| Melting point | >223°C (dec.) | | storage temp. | −20°C | | solubility | DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic |
| | beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt Usage And Synthesis |
| Description | Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most commonly leading to excretion in urine and bile. | | Chemical Properties | White to Off-White Solid | | Uses | A 17β-Estradiol (E888000) metabolite. | | References | [1] R RAFTOGIANIS. Estrogen metabolism by conjugation.[J]. Journal of the National Cancer Institute. Monographs, 2000, 27: 113-124. DOI: 10.1093/oxfordjournals.jncimonographs.a024234
[2] D W LOE. ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.[J]. The Journal of Biological Chemistry, 1996, 271 16: 9683-9689. DOI: 10.1074/jbc.271.16.9683 |
| | beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt Preparation Products And Raw materials |
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