- U-0521
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- $739.00
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2026-04-20
- CAS:5466-89-7
- Purity:
- Supply Ability: 10g
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| | 3',4'-Dihydroxy-2-methylpropiophenone Basic information |
| Product Name: | 3',4'-Dihydroxy-2-methylpropiophenone | | Synonyms: | 1-(3,4-dihydroxyphenyl)-2-methyl-1-propanon;3’,4’-dihydroxy-2-methyl-propiophenon;3’,4’-dihydroxy-isobutyrophenon;3’,4’-dihydroxyisobutyrophenone;U-0521;U-0521,98+%;1-(3,4-Dihydroxyphenyl)-2-methylpropan-1-one;3',4'-Dihydroxy-α-methylpropiophenone | | CAS: | 5466-89-7 | | MF: | C10H12O3 | | MW: | 180.2 | | EINECS: | | | Product Categories: | | | Mol File: | 5466-89-7.mol |  |
| | 3',4'-Dihydroxy-2-methylpropiophenone Chemical Properties |
| Melting point | 79-81℃ | | Boiling point | 372.2±27.0 °C(Predicted) | | density | 1.191±0.06 g/cm3(Predicted) | | RTECS | NQ5605000 | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | form | White solid. | | pka | 8.77±0.31(Predicted) | | color | Off-White to Pale Beige |
| | 3',4'-Dihydroxy-2-methylpropiophenone Usage And Synthesis |
| Uses | U-0521 is an extraneuronal COMT uptake inhibitor. | | Definition | ChEBI: U 0521 is a member of acetophenones. | | in vivo | U-0521 (i.p.; 0-250 mg/kg; 10 min) inhibits COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity is obtained at 90 mg/kg and maximum inhibition of 90% is obtained at 250 mg/kg[1]. | Animal Model: | Male Sprague-Dawley rats (180-250 g)[1] | | Dosage: | 0-250 mg/kg | | Administration: | i.p.; 10 min | | Result: | Inhibited COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity was obtained at 90mg/kg and maximum inhibition of 90% was obtained at 250 mg/kg. |
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| | 3',4'-Dihydroxy-2-methylpropiophenone Preparation Products And Raw materials |
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