- Boc-Aminooxy-PEG4-Tos
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2025-06-07
- CAS:1807539-01-0
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
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| | t-Boc-Aminoxy-PEG4-Tos Basic information |
| Product Name: | t-Boc-Aminoxy-PEG4-Tos | | Synonyms: | t-Boc-Aminoxy-PEG4-Tos;Boc-Aminooxy-PEG4-Tos;Boc-Aminoxy-PEG4-Tos;t-Boc-Aminooxy-PEG4-Tos;3,6,9,12-Tetraoxa-2-azatetradecanoic acid, 14-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;t-Boc-Aminooxy-PEG4-Tos boc | | CAS: | 1807539-01-0 | | MF: | C20H33NO9S | | MW: | 463.54 | | EINECS: | | | Product Categories: | | | Mol File: | 1807539-01-0.mol |  |
| | t-Boc-Aminoxy-PEG4-Tos Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Viscous Liquid | | color | Colorless to light yellow |
| | t-Boc-Aminoxy-PEG4-Tos Usage And Synthesis |
| Description | t-Boc-Aminooxy-PEG4-Tos is a bifunctional crosslinker reagent with a t-Boc-aminooxy group and a tosyl group. The tosyl group is a very good leaving group for nucleophilic substitution. The protected aminooxy can be deprotected under mild acidic conditions. PEG5 spacer increases solubility in aqueous media. | | Uses | Boc-Aminooxy-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | t-Boc-Aminoxy-PEG4-Tos Preparation Products And Raw materials |
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