(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid

(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Suppliers list

Company Name:	Shanghai Hongye Biotechnology Co. Ltd
Tel:	400-9205774 400-920-5774
Email:	sales@glpbio.cn

(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid manufacturers

(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Basic information

Product Name:	(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid
Synonyms:	CAY10443;(S)-INDAN-1-YL 3,4-DICHLOROBENZYLCARBAMATE;CKERQCMQSBFFKX-INIZCTEOSA-N;Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1S)-2,3-dihydro-1H-inden-1-yl ester (9CI);(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid
CAS:	582314-48-5
MF:	C17H15Cl2NO2
MW:	336.21
EINECS:
Product Categories:
Mol File:	Mol File

(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Chemical Properties

Boiling point	495.6±45.0 °C(Predicted)
density	1.36±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 30 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2)(1:2:): .25 mg/ml; Ethanol: 5 mg/ml
form	A crystalline solid
pka	11.15±0.46(Predicted)

Safety Information

MSDS Information

(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Usage And Synthesis

Uses	Apoptosis inducer 34 (Compound 4) is a small molecule compound that induces apoptosis by directly activating the intrinsic apoptotic pathway. Apoptosis inducer 34 promotes Apaf-1 oligomerization to form mature apoptosomes, thereby activating caspase-9 and caspase-3. It significantly activates the apoptotic pathway in Jurkat cells by enhancing the cytochrome c-dependent apoptotic signaling pathway, inducing PARP cleavage and chromosomal DNA fragmentation. Furthermore, Apoptosis inducer 34 exhibits low toxicity to normal cells, demonstrating potential for selective targeting of cancer cells. Apoptosis inducer 34 is a promising candidate for studying cancer related to apoptotic pathways[1].
Definition	ChEBI: Carbamic acid, [(3,4-dichlorophenyl)methyl]-, (1s)-2,3-dihydro-1h-inden-1-yl ester is a member of indanes.
References	[1] Nguyen JT, et al. Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7533-8. DOI:10.1073/pnas.1031631100

(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid Preparation Products And Raw materials

Tag:(1S)-2,3-Dihydro-1H-inden-1-yl ester [(3,4-dichlorophenyl)methyl]-carbamic acid(582314-48-5) Related Product Information

Gambogic acid 1-(3,4-Dichlorobenzyl)-1H-indole-2,3-dione 4H-Thiopyran-4-one,tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-1,1-dioxide PAC1 Ginsenoside CK Doxorubicin hydrochloride