| Company Name: |
BOC Sciences |
| Tel: |
16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
Commendamide manufacturers
- Commendamide
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- $1780.00
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2026-05-11
- CAS:193825-78-4
- Purity:
- Supply Ability: 10g
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| | Commendamide Basic information |
| Product Name: | Commendamide | | Synonyms: | Commendamide;Glycine, N-(3-hydroxy-1-oxohexadecyl)-;N-(3-hydroxy-1-oxohexadecyl)-glycine;Commendamide (N-acyl-3-hydroxypalmitoyl-Glycine) | | CAS: | 193825-78-4 | | MF: | C18H35NO4 | | MW: | 329.47 | | EINECS: | | | Product Categories: | | | Mol File: | 193825-78-4.mol |  |
| | Commendamide Chemical Properties |
| Boiling point | 532.5±35.0 °C(Predicted) | | density | 1.016±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3mg/ml; DMSO: 20 mg/ml; Ethanol: 15 mg/ml | | form | A crystalline solid | | pka | 3.51±0.10(Predicted) |
| | Commendamide Usage And Synthesis |
| Description | Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs).1 Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM.1 | | Uses | Commendamide is a GPCR G2A/GPR132 agonist (EC50: 11.8 μM). Commendamide can be used for research of autoimmunity and atherosclerosis[1]. | | Definition | ChEBI: N-(3-Hydroxy-1-oxohexadecyl)-glycine is a N-acyl-amino acid. | | References | 1. Cohen, L.J., Kang, H.S., Chu, J., et al. Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist Proc. Natl. Acad. Sci. USA 112(35),E4825-E4834(2015). |
| | Commendamide Preparation Products And Raw materials |
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