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Paclitaxel Ceribate [INN] manufacturers
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| | Paclitaxel Ceribate [INN] Basic information |
| | Paclitaxel Ceribate [INN] Chemical Properties |
| | Paclitaxel Ceribate [INN] Usage And Synthesis |
| Uses | Paclitaxel ceribate is the ester form of paclitaxel, a natural antineoplastic agent that stabilizes tubulin polymerization. Paclitaxel causes mitotic arrest and induces apoptosis, ultimately leading to cell death. Paclitaxel also induces autophagy[1][2]. | | References | [1] Choi YH, et al. Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. Oncol Rep. 2012 Dec;28(6):2163-9. DOI:10.3892/or.2012.2060
[2] Dziadyk JM, et al. Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest. Anticancer Res. 2004 Jan-Feb;24(1):27-36. PMID:15015572 |
| | Paclitaxel Ceribate [INN] Preparation Products And Raw materials |
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