Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester

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Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester manufacturers

  • NLRP3-IN-9
  • NLRP3-IN-9 pictures
  • $35.00
  • 2026-06-16
  • CAS:88039-46-7
  • Purity: 99.64%
  • Supply Ability: 10g
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Basic information
Product Name:Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester
Synonyms:Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester;Ethyl 2[(2-chlorophenyl)(hydroxy)methyl]acrylate;INF 4E;inflammasome,NOD-like Receptor (NLR),myocardial injury,NLRP3 IN 9,caspase-1,dysfunction,NLRP3IN9,Inhibitor,pyroptosis,inhibit,NLRP-3-IN-9,THP-1 cells;Benzenepropanoic acid, 2-chloro-β-hydroxy-α-methylene-, ethyl ester;NLRP3-IN-9, 10 mM in DMSO
CAS:88039-46-7
MF:C12H13ClO3
MW:240.68282
EINECS:
Product Categories:
Mol File:88039-46-7.mol
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Structure
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Chemical Properties
Boiling point 180-185 °C(Press: 10 Torr)
density 1.222±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka12.51±0.20(Predicted)
form Liquid
color Colorless to light yellow
Safety Information
MSDS Information
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Usage And Synthesis
UsesINF 4E was used to study the electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis.
in vivo

INF4E significantly reduces the in infarct size and lactate dehydrogenase release and improvement in postischemic left ventricular pressure[1].
INF4E attenuates the formation of NLRP3 inflammasome complex was induced by myocardial IR (ischemia/reperfusion) in a time-dependent way[1].

IC 50NLRP3
storageStore at -20°C
Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester Preparation Products And Raw materials
Tag:Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester(88039-46-7) Related Product Information
Benzenepropanoic acid, 2-chloro-β-hydroxy-, ethyl ester, (βS)- Ethyl 2,4-dichloro-β-hydroxybenzenepropanoate ethyl 2-[(4-chlorophenyl)(hydroxy)methyl]prop-2-enoate 2-(Hydroxy-phenyl-methyl)-acrylic acid methyl ester 2-[(4-Chloro-phenyl)-hydroxy-methyl]-acrylic acid methyl ester Benzenepropanoic acid, 2-chloro-b-hydroxy-a-methylene-, ethyl ester