137004-80-9
| 中文名称 | 137004-80-9 |
|---|---|
| 中文同义词 | 化合物 T12404;CCK-A受体抑制剂1 |
| 英文名称 | Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo- |
| 英文同义词 | Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-;CCK-A receptor inhibitor 1;CCK A receptor inhibitor 1,CCKA receptor inhibitor 1 |
| CAS号 | 137004-80-9 |
| 分子式 | C25H35NO6S |
| 分子量 | 477.6135 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 137004-80-9.mol |
| 结构式 |  |
137004-80-9 性质
| 沸点 | 705.1±60.0 °C(Predicted) |
|---|---|
| 密度 | 1.187±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 酸度系数(pKa) | 4.47±0.10(Predicted) |
CCK-A receptor inhibitor 1 是一种缩胆囊素 A (cholecystokinin A, CCK-A) 受体抑制剂，IC50 为 340 nM。
IC50: 340 nM (CCK-A receptor)
CCK-A receptor inhibitor 1 (Compound 7c) is a naphthyl sulfone derivative, which is synthesized and tested for cholecystokinin A (CCK-A) receptor inhibitory activity in order to study structure-activity relationships. Significant CCK-A receptor inhibitory activities are found in CCK-A receptor inhibitor 1 having very hydrophobic sidechains.