| Company Name: |
TCI Europe |
| Tel: |
320-37350700 |
| Email: |
sales@tcieurope.eu |
| Company Name: |
TCI AMERICA |
| Tel: |
800-4238616 |
| Email: |
sales@tciamerica.com |
BTT 3033 manufacturers
- BTT-3033
-
- $108.00
-
2026-07-27
- CAS:1259028-99-3
- Purity: 99.36%
- Supply Ability: 10g
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| | BTT 3033 Basic information |
| Product Name: | BTT 3033 | | Synonyms: | BTT 3033;1-(4-Fluoro-phenyl)-1H-pyrazole-4-sulfonic acid methyl-[4-(3-phenyl-ureido)-phenyl]-amide;1-(4-Fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide;1-(4-Fluorophenyl)-N-methyl-N-(4-(3-phenylureido)phenyl)-1H-pyrazole-4-sulfonamide;1H-Pyrazole-4-sulfonamide, 1-(4-fluorophenyl)-N-methyl-N-[4-[[(phenylamino)carbonyl]amino]phenyl]-;1-(4-Fluorophenyl)-N-methyl-N-(4-(3-phenylureido)phenyl)-1H-pyrazole-4-sulfonamide , BTT-3033;3-{4-[N-methyl-1-(4-fluorophenyl)-1H-pyrazole-4-sulfonamido]phenyl}-1-phenylurea | | CAS: | 1259028-99-3 | | MF: | C23H20FN5O3S | | MW: | 465.5 | | EINECS: | | | Product Categories: | | | Mol File: | 1259028-99-3.mol |  |
| | BTT 3033 Chemical Properties |
| density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | powder to crystal | | pka | 13.78±0.70(Predicted) | | color | White to Light yellow to Light orange |
| | BTT 3033 Usage And Synthesis |
| Uses | BTT 3033acts as a selective inhibitor of integrin, preventing platelet aggregation and potential application towards tumor suppression. | | in vivo | BTT-3033 (oral administration, 10 mg/kg, at 24 h and 2 h before PAF induction) shows anti-inflammatory effects in mouse air pouch model[2].
BTT-3033 (oral administration, 10 mg/kg, at 48 ,24 and 2 h before ear swelling) shows anti-inflammatory effects in arachidonic acid-induced ear edema model[2]. | Animal Model: | PAF (platelet-activating factor)-induced mouse air pouch model[2] | | Dosage: | 1, 10 mg/kg at 24 h and 2 h before PAF induction | | Administration: | Oral administration | | Result: | Reduced the infiltration of leukocytes by about 50% at 10 mg/kg. |
| Animal Model: | Male DBA/1 mice (Pharmacokinetic assay)[2] | | Dosage: | 10 mg/kg for a single dose | | Administration: | Oral administration | | Result: | Plasma levels: about 1 ng/mL at 24 h post-dose. |
| | IC 50 | α2β1: 130 nM (EC50) | | storage | Store at +4°C |
| | BTT 3033 Preparation Products And Raw materials |
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