| Company Name: |
InvivoChem Gold |
| Tel: |
13549236410 |
| Email: |
sales@invivochem.cn |
diphenylterazine manufacturers
- Diphenylterazine
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- $30.00
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2026-07-16
- CAS:344940-63-2
- Purity: 99.89%
- Supply Ability: 10g
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| | diphenylterazine Basic information |
| Product Name: | diphenylterazine | | Synonyms: | diphenylterazine;Imidazo[1,2-a]pyrazin-3(7H)-one, 6,8-diphenyl-2-(phenylmethyl)-;Diphenylterazine (DTZ);Inhibitor,Diphenylterazine,inhibit;2-Benzyl-6,8-diphenylimidazo[1,2-a]pyrazin-3(7H)-one;DTZ | | CAS: | 344940-63-2 | | MF: | C25H19N3O | | MW: | 377.44 | | EINECS: | | | Product Categories: | | | Mol File: | 344940-63-2.mol |  |
| | diphenylterazine Chemical Properties |
| Boiling point | 538.4±60.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | solubility | DMSO:75.0(Max Conc. mg/mL);198.71(Max Conc. mM)
DMF:11.11(Max Conc. mg/mL);29.44(Max Conc. mM) | | form | A solid | | pka | 6.33±0.40(Predicted) | | color | Orange to reddish brown | | InChI | InChI=1S/C25H19N3O/c29-25-21(16-18-10-4-1-5-11-18)27-24-23(20-14-8-3-9-15-20)26-22(17-28(24)25)19-12-6-2-7-13-19/h1-15,17,26H,16H2 | | InChIKey | HYQVAZNNCBIZSK-UHFFFAOYSA-N | | SMILES | C12N=C(CC3=CC=CC=C3)C(=O)N1C=C(C1=CC=CC=C1)NC=2C1=CC=CC=C1 |
| | diphenylterazine Usage And Synthesis |
| Uses | Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios[1]. | | in vivo | Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission. The bioluminescence resulting from intraperitoneally injected Diphenylterazine displays extended kinetics[1].
DTZ (0.3 μmol/mouse (1.13 mg.ml-1/100 ul/mouse); i.v.) treatment can track tumor growth in a xenograft NU/J mouse model[4]. | | References | [1] Yeh HW, et al. Red-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging. Nat Methods. 2017 Oct;14(10):971-974. DOI:10.1038/nmeth.4400
[2] Yeh AH, et al. De novo design of luciferases using deep learning. Nature. 2023 Feb;614(7949):774-780. DOI:10.1038/s41586-023-05696-3
[3] Practical Notes for teLuc-DTZ and Antares2-DTZ (updated 07/29/2019).
[4] Hsien-Wei Yeh, et al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019 May 17;14(5):959-965. DOI:10.1021/acschembio.9b00150 |
| | diphenylterazine Preparation Products And Raw materials |
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