Ald-Ph-PEG2-t-butyl ester

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Ald-Ph-PEG2-t-butyl ester Basic information
Product Name:Ald-Ph-PEG2-t-butyl ester
Synonyms:Ald-Ph-PEG2-Boc;Ald-Phenyl-PEG2-t-butyl ester;Propanoic acid, 3-[2-(4-formylphenoxy)ethoxy]-, 1,1-dimethylethyl ester;tert-Butyl 3-[2-(4-formylphenoxy)ethoxy]propanoate
CAS:2100306-65-6
MF:C16H22O5
MW:294.34
EINECS:
Product Categories:
Mol File:2100306-65-6.mol
Ald-Ph-PEG2-t-butyl ester Structure
Ald-Ph-PEG2-t-butyl ester Chemical Properties
Boiling point 414.4±30.0 °C(Predicted)
density 1.102±0.06 g/cm3(Predicted)
Safety Information
MSDS Information
Ald-Ph-PEG2-t-butyl ester Usage And Synthesis
DescriptionAld-Ph-PEG2-t-butyl ester is a PEG linker with an aldehyde functional group. The t-butyl ester can be removed under acidic conditions.
UsesAld-Ph-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs; Alkyl/ether
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Ald-Ph-PEG2-t-butyl ester Preparation Products And Raw materials
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