| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
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| | HIFJCPQKFCZDDL-UGQITTIWSA-N Basic information |
| Product Name: | HIFJCPQKFCZDDL-UGQITTIWSA-N | | Synonyms: | HIFJCPQKFCZDDL-UGQITTIWSA-N;Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5Z)- (9CI);6,9α-methylene-11α,15S-dihydroxy-16-methyl-prosta-5Z,13E-dien-18-yn-1-oic acid;Iloprost Impurity 40;(Z)-Iloprost | | CAS: | 82889-99-4 | | MF: | C22H32O4 | | MW: | 360.49 | | EINECS: | | | Product Categories: | | | Mol File: | 82889-99-4.mol |  |
| | HIFJCPQKFCZDDL-UGQITTIWSA-N Chemical Properties |
| Boiling point | 539.2±50.0 °C(Predicted) | | density | 1.210±0.06 g/cm3(Predicted) | | solubility | DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 1 mg/ml | | pka | 4.77±0.10(Predicted) |
| | HIFJCPQKFCZDDL-UGQITTIWSA-N Usage And Synthesis |
| Description | 5-cis Iloprost is the C-5 cis-isomer of iloprost, a second generation structural analog of prostaglandin I2 (prostacyclin). Iloprost displays ten-fold greater potency than the first generation stable prostacyclin analogs, typified by carbaprostacyclin.1 There are no published studies of the pharmacological properties of 5-cis iloprost. | | Uses | (Z)-Iloprost ((Z)-Ciloprost; (Z)-ZK 36374) is a vasodilator that prevents heparin-induced platelet activation[1][2][3]. | | References | 1. Schrr, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) — equipotent to PGI2 in vitro Naunyn Schmiedebergs Arch. Pharmacol. 316(3),252-255(1981). |
| | HIFJCPQKFCZDDL-UGQITTIWSA-N Preparation Products And Raw materials |
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