- CYCLOHEXYL ISOCYANIDE
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- $100.00 / 1KG
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2025-09-25
- CAS:931-53-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Cyclohexyl isocyanide
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- $1.00 / 1KG
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2020-01-08
- CAS: 931-53-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20T
- CYCLOHEXYL ISOCYANIDE
-
- $2.00 / 1KG
-
2020-01-08
- CAS:931-53-3
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 100g , 1kg, 5kg , 50kg
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| | CYCLOHEXYL ISOCYANIDE Basic information |
| Product Name: | CYCLOHEXYL ISOCYANIDE | | Synonyms: | Cyclohexane, isocyano-;Cyclohexaneisonitrile;BIO-FARMA BF001328;ISOCYANOCYCLOHEXANE;HANSA ISN-0519;CYCLOHEXYL ISOCYANIDE;CYCLOHEXYL ISONITRILE;Cyclohexyl #niso-cyanide | | CAS: | 931-53-3 | | MF: | C7H11N | | MW: | 109.17 | | EINECS: | 213-238-7 | | Product Categories: | ISONITRITE | | Mol File: | 931-53-3.mol |  |
| | CYCLOHEXYL ISOCYANIDE Chemical Properties |
| Melting point | 6.45°C | | Boiling point | 173-176 °C | | density | 0.878 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.45(lit.) | | Fp | 170 °F | | storage temp. | Store at +2°C to +8°C. | | form | Liquid | | color | Clear colorless to slightly brown | | BRN | 3662332 | | Stability: | Stable. Incompatible with strong acids, strong bases, strong reducing agents, strong oxidizing agents. Flammable. | | InChI | InChI=1S/C7H11N/c1-8-7-5-3-2-4-6-7/h7H,2-6H2 | | InChIKey | XYZMOVWWVXBHDP-UHFFFAOYSA-N | | SMILES | C1([N+]#[C-])CCCCC1 | | CAS DataBase Reference | 931-53-3(CAS DataBase Reference) |
| Hazard Codes | Xn,T | | Risk Statements | 20/21/22-23/24/25 | | Safety Statements | 36/37-45-24/25 | | RIDADR | UN 2810 6.1/PG 2 | | WGK Germany | 3 | | F | 10-13-21 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29299090 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral |
| | CYCLOHEXYL ISOCYANIDE Usage And Synthesis |
| Chemical Properties | colourless liquid | | Uses | Cyclohexyl Isocyanide can be used as novel arginase inhibitors to treat diseases. | | Preparation | CAUTION: Use a well-ventilated hood and take all precautions before using phosgene.
To a flask equipped as in Preparation 3-1 is added 1.27 kg (10.0 moles) of N-cyclohexylformamide, 3.20 liters of triethylamine, and 4.50 liters of methylene chloride. The solution is stirred while phosgene is rapidly added (300-400 gm/hr) to cause vigorous refluxing. Refluxing ceases after 1.04 kg (10.2 moles) of phosgene have been added and the addition is stopped. The reaction mixture is cooled to 22-25°C, 400 gm (23.5 moles) of ammonia gas added over a period of 1-2 hr, the mixture filtered then concentrated under reduced pressure, and the residue distilled to afford 955 gm (88%), b.p. 67-72°C (14 mm Hg).
 | | Definition | ChEBI: Cyclohexyl isocyanide is an isocyanide having a cyclohexyl group attached to nitrogen. It is a conjugate base of a cyclohexyl isocyanide(1+). | | General Description | Cyclohexyl isocyanide reacts with dimethyl acetylenedicarboxylate to give a mixture of cyclopenta[b]pyridine derivatives, azaspirononatriene derivative and the azabicyclononatriene. It reacts with dialkyl acetylenedicarboxylates to form 1:1 intermediate which on facile addition to 1-benzylisatin and tryptantrin yields highly functionalized novel unsaturated γ-spiroiminolactones. | | References |
[1] Khalili, Gholamhossein. “ChemInform Abstract: A Diastereoselective Synthesis of (Z)-3-[(Aryl)(hydroxyimino)methyl] -2-cyclohexyl-1-(cyclohexylamino)imidazo[5,1-a]isoquinolinium Chlorides from Isoquinoline, Chlorooximes, and Cyclohexyl Isocyanide.” ChemInform 47 25 (2016).
[2] M. Anary‐Abbasinejad, M. Heidari, N. Shams. “One-pot synthesis of highly functionalised 1H-pyrazoles from arylcarbohydrazides, cyclohexyl isocyanide, and acetylene diesters.” Arkivoc 2012 1 (2012).
[3] Anary‐Abbasinejad, M. M. Jaafari and Mahdiyeh Talebizadeh. “One-pot Four-component Reaction between Arylamines, Arylglyoxals, Cyclohexyl Isocyanide, and Acetylene Diesters: An Efficient Synthesis of 2H-iminopyran Derivatives.” 2019. 0.
[4] Alireza Hassanabadi. “ChemInform Abstract: Use of Cyclohexyl Isocyanide in the Esterification of N-Benzoyl α-Amino Acid Derivatives.” ChemInform 43 3 (2011).
[5] A. Hassanabadi. “The use of cyclohexyl isocyanide in the esterification of N -benzoyl α-amino acids derivatives.” Journal of Chemical Research-s 18 1 (2011): 468–470.
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| | CYCLOHEXYL ISOCYANIDE Preparation Products And Raw materials |
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