N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide

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N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:MGH-CP1
CAS:896657-58-2
Purity:98.66% Package:2mg;34USD|5mg;55USD|10mg;89USD
Company Name: BOC Sciences
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Products Intro: Product Name:MGH-CP1
CAS:896657-58-2
Package:100 mg Remarks:Please reach out to us for more information about custom solutions.
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
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Products Intro: Product Name:MGH-CP1
CAS:896657-58-2
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
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Products Intro: Product Name:N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide
CAS:896657-58-2
Purity:0.98 Package:100mg;500mg;1g;5g Remarks:existing product
Company Name: Aladdin Scientific
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Products Intro: Product Name:MGH-CP1
CAS:896657-58-2
Purity:98% Package:$166.9/5mg;$266.9/10mg;$533.9/25mg;$866.9/50mg;$1399.9/100mg;$2799.9/250mg;Bulk Remarks:98%

N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide manufacturers

  • MGH-CP1
  • MGH-CP1 pictures
  • $34.00
  • 2026-07-17
  • CAS:896657-58-2
  • Purity: 99.76%
  • Supply Ability: 10g
N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide Basic information
Product Name:N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide
Synonyms:N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide;2-((1H-1,2,4-Triazol-5-yl)thio)-N-(4-(adamantan-1-yl)phenyl)acetamide;N-?[4-?(1-?Adamantyl)?phenyl]?-?2-?(4H-?1,?2,?4-?triazol-?3-?ylsulfanyl)?acetamide;MGH CP1,Lats1/2 deletion,Myc,MGHCP1,TEAD auto-palmitoylation,Apoptosis,Epithelial,MGH-CP1,inhibit,Inhibitor,MGH-CP-1;MGH-CP1, 10 mM in DMSO;MGH-CP1 ，S9735
CAS:896657-58-2
MF:C20H24N4OS
MW:368.49576
EINECS:816-922-9
Product Categories:
Mol File:896657-58-2.mol
N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide Structure
N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide Chemical Properties
storage temp. 4°C, away from moisture and light
form Solid
color White to off-white
InChIInChI=1S/C20H24N4OS/c25-18(11-26-19-21-12-22-24-19)23-17-3-1-16(2-4-17)20-8-13-5-14(9-20)7-15(6-13)10-20/h1-4,12-15H,5-11H2,(H,23,25)(H,21,22,24)
InChIKeyUUKXOVBCMOZQNC-UHFFFAOYSA-N
SMILESC(NC1=CC=C(C23CC4CC(CC(C4)C2)C3)C=C1)(=O)CSC1NC=NN=1
Safety Information
MSDS Information
N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide Usage And Synthesis
UsesN-[4-(1-Adamantyl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide acts as a TEAD transcription factor autopalmitoylation inhibitor which may be a therapeutical treatment for certain cancers.
in vivo

MGH-CP1 (75mg/kg; PO; daily, for 2 weeks) inhibits the palmitoylation of TEAD proteins in the intestinal epithelium in wild-type mice, but inhibits upregulation of the TEAD target genes, CTGF and ANKRD1, in Lats1/2 KO mice intestine[1].

Animal Model:Mice (induced high-dose Cre recombination by intraperitoneal injection of 120mg/kg Tamoxifen for two consecutive days)[1]
Dosage:75 mg/kg
Administration:PO; daily, for 2 weeks
Result:Effectively inhibited the palmitoylation of TEAD proteins in the intestinal epithelium in wild-type mice, but effectively inhibited upregulation of the TEAD target genes, CTGF and ANKRD1, in Lats1/2 KO mice intestine.
N-[4-(adamantan-1-yl)phenyl]-2-(4H-1,2,4-triazol-3-ylsulfanyl)acetamide Preparation Products And Raw materials
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